Snail2 is an Essential Mediator of Twist1-Induced Epithelial Mesenchymal Transition and Metastasis
نویسندگان
چکیده
منابع مشابه
Snail2 is an essential mediator of Twist1-induced epithelial mesenchymal transition and metastasis.
To metastasize, carcinoma cells must attenuate cell-cell adhesion to disseminate into distant organs. A group of transcription factors, including Twist1, Snail1, Snail2, ZEB1, and ZEB2, have been shown to induce epithelial mesenchymal transition (EMT), thus promoting tumor dissemination. However, it is unknown whether these transcription factors function independently or coordinately to activat...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2011
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-10-2330